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HOME/PEOPLE/GUIDO APPENZELLER
// PERSON

Guido Appenzeller

ROLE GENERAL PARTNERAT A16ZMENTIONS 2LAST SEEN OCTOBER 9, 2026
// BIO

Guido Appenzeller is a Partner at Andreessen Horowitz (a16z), where he focuses on AI, infrastructure, open source technology, and silicon investments. He previously served as CTO of Intel's Data Center & AI business unit and as CTO of Cloud & Networking at VMware. He is best known for co-founding Big Switch Networks and Voltage Security, co-developing the OpenFlow v1.0 protocol, and publishing the widely cited "LLMflation" analysis on AI inference cost trends.

Discussed in
// RECENT MENTIONS
// SIGNALS
2 SIGNALS
01
mention·The a16z Show·OCTOBER 9, 2026

“The agents will do all the upgrades. So, that's no longer a problem... Everything gets easy”

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02
mention·The a16z Show·AUGUST 30, 2026

“Guido Appenzeller, who is actually the former CTO of Intel, is also someone who is very, very technical, sold into and ran kind of the data center business for Intel as well.”

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AI-extracted from podcast / newsletter / paper summaries. May contain errors.

Guido Appenzeller · General Partner at a16z — 2 mentions on Teahose