Priscilla Chan

“with a $500M commitment to the Virtual Biology Initiative. Building hierarchical world models of biology combining frontier AI with frontier wet-lab science.”

“We were all inspired by baby KJ, when the team at CHOP was able to deliver a CRISPR therapeutic to edit a mutation that he had... because we needed to target his liver cells.”

“We partner with Jennifer Doudna on a CRISPR Cures program at UCSF.”

“What if we could actually understand how biology worked? Move it from a discovery-based science to an engineering-based science where we could systematically understand how living beings, living cells worked and be able to understand why things go wrong. And so when we saw that moment, we were like, this is it. Something really big could happen here.”

“Biohub's ESMFold2 release demonstrates that scaling laws apply to protein biology models just as they do to language models, and that inference-time scaling is now delivering real laboratory results.”

“This is what Chan Zuckerberg Initiative is working on. They're trying to figure out computational bio on the cell level and then on the organ level and then the system level.”