David Friedberg

“Friedberg added the sharp version: 'the market is AI, it turns out... this deal is 1% and 0.2% of the market.'”

“I think what we're watching is probably the birth of a new religion”

“David Friedberg... whose hottest take answer at the Hill and Valley Forum went completely viral”

“there was one medical there was forward. I mean, there were a few other kind of attempts at making these integrated centers where you go in and get preventative checkups with their own instrumentation.”

“Today, a Cray supercomputer, I think, is less power than a washing machine or something.”

“compute as a key metric of defensibility, and that's really where we can start to build guardrails around who can have access to the most compute and how do you get certified for compute as opposed to certified for software.”

“David Friedberg — Referenced by Molly O'Shea as a recent podcast guest who discussed how the US tax system inverts optimal incentives.”

“As soon as open source is banned, you have now created a monopoly that is in partnership with the federal government.”

“This is a doomer psyop and the ultimate target is open source... that is what an FDA will ultimately ban.”

“On the K-shaped economy Ray Dalio raised in their March conversation, Friedberg reframed the divergence as wealth rather than jobs.”

“Billionaires hold ~$8T of a $183T household net worth base... The problem is not that the rich took the poor's assets; it's that the poor were structurally excluded from ever owning productive assets in the first place.”

“If you had put all the extra money that was put into Social Security since 1982 into the S&P 500, the Social Security Trust Fund would have an extra $37 trillion in assets sitting in it today.”

“Joe Lonsdale has made a version of the same point, that he is rich but would pay 90% in taxes if it actually worked. Friedberg agreed on the same condition — if the money actually produces results.”

“Eliminating income tax entirely for the bottom 50% of earners, roughly those under $75,000 per year, a proposal put forward by Jeff Bezos.”

“If you had put all the extra money that was put into Social Security since 1982 into the S&P 500, the Social Security Trust Fund would have an extra $37 trillion in assets sitting in it today.”

“Stripe Wants PayPal... Who better than Stripe? And maybe Jack Dorsey plays a role here... I think it's a shot across the bow for Visa and MasterCard.”

“He bought Evernote and he just goes in and he diagnoses these businesses. He's like, where are you overspending? Where are you underspending? What are you doing wrong with the product? And what are you doing wrong with marketing? And he just fixes it. And he's just a killer. And he's taken all of these, what were called web 2.0 businesses, and he's revitalized them, rolled them up and printing cash out of them.”

“Folks that are, call it AI native, are looking at, call it first generation digital native businesses that have become mature and old and stale and aren't run by the founders anymore and have not yet realized the opportunities with AI... I think that eBay and PayPal are probably the beginning of a wave of mega deals of, call it flaccid, digital businesses... that can be revived with the blue chew of capital and the right operator.”

“They were able to eliminate 55% of the CML on the skin, which basically reversed the skin's age down to the age of a 31-year-old. This is from greater than 70-year-old patients, just by putting this enzyme on the skin.”

“Prior to Russia Today existing in the U.S., there was no anti-GMO sentiment... and you can actually see this on the Google Trend data... you can trace it back to the same people that in a different era were protesting fracking.”

“"When you use our harness with Claude, it was simultaneously 1.4x cheaper and 1.5x faster than just using Anthropic Opus 48 alone. But if you wrap the open source model with our software factory, it was 16.4x cheaper."”

“"This is all using OpenRouter on a very traditional hardware stack."”

“"The top 1,000 people in the state of California pay roughly $22 billion a year. So more than 11% of the state's income... We are seeing an average annual exodus of one to one and a half percent of personal income leaving the state every year right now. That might not sound like a lot, but after 10 years, you've seen 15% of the state's income leave."”

“"California's state budget ballooned from $215 billion a year in 2019 to $355 billion today. So a 65% jump in the state budget... In the out years 2028-29, the projection is $40 billion a year in budget deficits every year."”

“"If you are a reasonable company, why are you not finding an independent way to access this intelligence in a way that doesn't leak your edge away? To do so at this point now is kind of becoming derelict and irresponsible."”

“The ARC Institute ingested all the world's genomic data that they could get access to. And it's a genome language model, basically... It's figured out the language of DNA.”

“I think with the Kevin Warsh Fed I think we could see north of future of our monetary policy.”

“The idea that you can regulate or downscale or turn off AI is not a realistic idea. The models have been put out in the world. It's like publishing a book.”

“There is no job loss with AI. I will say it again. I've said it a thousand times... The idea that AI is going to destroy jobs is a Luddite idea that is being disproven every single day.”

“It's a good example where a community, in this case, the Collisons and others, put money behind it to fund this research and output this open source model.”